Zakażenie SARS-CoV-2 i cukrzyca: doświadczenie w północno-wschodniej Rumunii

Rozprzestrzeniając się na całym świecie, nowy wirus SARS-CoV-2 został po raz pierwszy potwierdzony w Rumunii w lutym 2020 r., Nieuchronnie infekując osoby z cukrzycą (DM) po drodze. Wiadomo, że cukrzyca wpływa na odpowiedź organizmu na patogeny, a z badań przeprowadzonych w ciągu ostatnich 3 miesięcy wynika, że ​​chorzy na cukrzycę są bardziej narażeni na rozwój ciężkich postaci choroby i wielu powikłań.

Przeprowadziliśmy retrospektywne badanie w celu oceny pacjentów z zakażeniem SARS-CoV-2 i cukrzycą przyjętą do „Sf. Szpital Kliniczny Chorób Zakaźnych Parascheva od 4 marca do 30 czerwca 2020 r. Z ogólnej liczby 1080 pacjentów przyjętych w tym okresie 85 pacjentów (7,87%) miało współistniejącą postać DM, głównie typu 2 (82 przypadki, 96,46%); średni wiek tych pacjentów wynosił 62 lata, a mężczyźni 42 (49,41%).

TK klatki piersiowej ujawniły orientacyjne obrazy SARS-CoV-2 u wszystkich pacjentów, a ich leczenie obejmowało indywidualnie dostosowane podanie hydroksychlorochiny / lopinawiru + rytonawiru / enoksaparyny sodowej / tocilizumabu / antybioterapii zgodnie z wytycznymi krajowymi i międzynarodowymi. W sumie 70 pacjentów (82,35%) zostało wyleczonych, a 15 zmarło na MODS i / lub związaną z nim neoplazję, co doprowadziło do śmiertelności do 17,64%. Chociaż zaawansowany wiek i cukrzyca były związane z zaostrzonymi postaciami zakażenia SARS-CoV-2, ponad 80% pacjentów włączonych do niniejszego badania zostało wyleczonych. Niemniej jednak cukrzyca wydaje się być istotnym predyktorem zachorowalności i śmiertelności w przypadku zakażenia SARS-CoV-2.

MicroRNA-1323 służy jako biomarker w cukrzycy ciążowej i pogarsza indukowane przez glukozę hamowanie żywotności komórek trofoblastów poprzez tłumienie TP53INP1

Cukrzyca ciążowa (GDM) prowadzi do złych wyników ciąży, a mikroRNA (miRNA / miR) są sugerowane jako związane z GDM, ale mechanizmy patologiczne pozostają niejasne. Niniejsze badanie miało na celu zbadanie wartości diagnostycznej miR-1323 u pacjentów z GDM i jego wpływu na żywotność komórek trofoblastu. Ponadto w niniejszym badaniu zbadano korelację między miR-1323 i TP53INP1, aby zrozumieć patologiczny mechanizm progresji GDM. Do wykrycia ekspresji miR-1323 i ekspresji mRNA TP53INP1 zastosowano ilościową reakcję łańcuchową polimerazy z odwrotną transkrypcją.

Wartość diagnostyczną miR-1323 w surowicy oceniono za pomocą analizy charakterystyki operacyjnej odbiornika. Komórki HTR-8 / SVneo i BeWo traktowano wysoką zawartością glukozy (HG) w celu skonstruowania modeli komórkowych GDM, a żywotność komórek trofoblastów oceniano przy użyciu testu MTT. Ekspresję białka TP53INP1 wykryto za pomocą analizy Western blot.

Korelację między miR-1323 i TP53INP1 zbadano za pomocą testu reporterowego lucyferazy. Ekspresja miR-1323 była zwiększona u pacjentów z GDM, która miała stosunkowo wysoką dokładność diagnostyczną w badaniach przesiewowych GDM i była dodatnio skorelowana z glikemią na czczo u pacjentów z GDM. HG zwiększał ekspresję miR-1323 i hamował żywotność komórek trofoblastów. Nadekspresja miR-1323 znacząco hamowała żywotność komórek trofoblastu indukowanych przez HG. TP53INP1, gen docelowy miR-1323, był ujemnie skorelowany z miR-1323.

Nadekspresja TP53INP1 odwróciła hamujący wpływ nadekspresji miR-1323 na żywotność komórek trofoblastu traktowanych HG. Podwyższone poziomy miR-1323 w surowicy mogą być biomarkerem diagnostycznym GDM. Dodatkowo miR-1323 może hamować żywotność komórek trofoblastów poprzez hamowanie TP53INP1, co sugeruje, że może być potencjalnym celem terapeutycznym dla GDM.

Rola terapii skojarzonej z podbakteryjnymi dawkami doksycykliny w kontroli glikemii (HbA1c) u chorych na cukrzycę i zmiany endo-przyzębia w zapobieganiu powikłaniom zatokowym

Niniejsze badanie miało na celu analizę lokalnych i regionalnych zmian w odniesieniu do zębopochodnego zapalenia zatok u pacjentów ze zmianami endo-przyzębia i cukrzycą oraz zbadanie wpływu na poziom kontroli glikemii (hemoglobina glikowana), który może być wywołany przez terapię wspomagającą dawkami subantybiotykowymi. doksycykliny. W badaniu wzięło udział 51 pacjentów z cukrzycą, którzy zostali podzieleni na dwie grupy terapeutyczne: 31 pacjentów z cukrzycą (grupa badana), którzy przeszli konwencjonalną terapię endo-periodontologiczną i sub-przeciwdrobnoustrojowe dawki doksycykliny oraz 20 pacjentów z cukrzycą, którzy byli leczeni wyłącznie terapia (grupa kontrolna).

Pacjentów poddano badaniu klinicznemu endodontycznemu i periodontologicznemu, z wykonaniem zdjęć radiologicznych poza zębodołowych i CBCT. Dla każdego pacjenta oznaczono hemoglobinę glikowaną A1c (HbA1c). Oceny tej dokonano na początku badania, a także 3, 6 i 12 miesięcy po rozpoczęciu badania. Znaczący odsetek pacjentów, zarówno w grupie badanej, jak iw grupie kontrolnej, wykazywał radiologiczne objawy zębopochodnego zapalenia zatok, łącznie 29 pacjentów (56,86%).

Parametry przyzębia ujawniły niższe poziomy u pacjentów poddanych reżimowi składającemu się z sub-przeciwdrobnoustrojowych dawek doksycykliny; wyniki te utrzymywały się przez cały okres badania. Ponadto wykazaliśmy znacząco obniżone poziomy hemoglobiny glikowanej w trakcie badania (12 miesięcy) w grupie leczonej doksycykliną. Fakt ten ma daleko idące skutki również w zakresie powikłań lokoregionalnych, a ryzyko zębopochodnego zapalenia zatok może być znacznie zmniejszone.

Rekombinowany Lactococcus lactis niosący wektory kodujące IL-4 i IL-10 chroni przed cukrzycą typu 1 u myszy NOD i łagodzi zapalenie insuliny w modelu indukowanym STZ

Cukrzyca typu 1 (T1D) jest chorobą autoimmunologiczną, której kulminacją jest zniszczenie komórek beta trzustki, a następnie niedobór produkcji insuliny. Cytokiny odgrywają kluczową rolę w rozwoju cukrzycy, koordynując rekrutację i działanie komórek odpornościowych, aby nie tylko niszczyć komórki produkujące insulinę, ale także je chronić. Dlatego celem tego badania było zbadanie wpływu doustnie podawanych szczepów Lactococcus lactis MG1363 FnBPA + niosących plazmidy kodujące IL-4 i IL-10 w modelu cukrzycy indukowanej streptozotocyną (STZ-) oraz u nieotyłych myszy z cukrzycą (NOD).

Myszy indukowane STZ, które były leczone połączonymi szczepami bakteryjnymi niosącymi plazmidy kodujące IL-4 i IL-10, wykazywały mniejszą częstość występowania cukrzycy i bardziej zachowane wysepki trzustkowe niż myszy, które otrzymały poszczególne szczepy bakteryjne. Połączone podawanie L. lactis MG1363 FnBPA + (pValac :: dts :: IL-4) i L. lactis MG1363 FnBPA + (pValac :: IL-10) skutkowało ochroną przed cukrzycą u myszy NOD. Wykazano, że skojarzone leczenie rekombinowanymi bakteriami drogą doustną zapobiegło hiperglikemii i zmniejszyło destrukcję wysp trzustkowych u myszy NOD. Ponadto zwiększone poziomy IL-4 i IL-10 w surowicy i tkance trzustki ujawniły ogólnoustrojowy efekt leczenia, a także sprzyjały mikrośrodowisku przeciwzapalnemu. Zmniejszone stężenia IL-12 w trzustce miały zasadnicze znaczenie dla regulacji stanu zapalnego, skutkując brakiem występowania cukrzycy u leczonych myszy NOD.

Human Kit ligand (KITLG) ELISA Kit
abx253483-96tests	Abbexa	96 tests	EUR 801.6

Cow Kit ligand (KITLG) ELISA Kit
abx511856-96tests	Abbexa	96 tests	EUR 1093.2

Chicken Kit ligand (KITLG) ELISA Kit
abx511857-96tests	Abbexa	96 tests	EUR 1093.2

Dog Kit ligand (KITLG) ELISA Kit
abx511858-96tests	Abbexa	96 tests	EUR 1093.2

Mouse Kit ligand (KITLG) ELISA Kit
abx511860-96tests	Abbexa	96 tests	EUR 801.6

Pig Kit ligand (KITLG) ELISA Kit
abx511861-96tests	Abbexa	96 tests	EUR 1093.2

Rat Kit ligand (KITLG) ELISA Kit
abx511862-96tests	Abbexa	96 tests	EUR 801.6

Human Kit Ligand, KitLG ELISA Kit
DEIA141	Creative Diagnostics	10 plates	EUR 2994
Description: Human KITLG ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant KITLG in a sandwich ELISA format within the range of 16-2,000 pg/mL. Using the ELISA protocol described below, this kit provides sufficient reagents to assay KITLG in approximately 1,000 ELISA plate wells

Rat Kit Ligand, Kitlg ELISA Kit
DEIA142	Creative Diagnostics	10 plates	EUR 2994
Description: The Human DKK1 ELISA kit is for the quantitative determination of Human DKK1.;This ELISA kit contains the basic components required for the development of sandwich ELISAs. Each kit contains sufficient materials to run ELISAs on five 96-well plates.

Rat Kitlg/ Kit ligand ELISA Kit
E0545Ra	Sunlong	1 Kit	EUR 655.2

Rabbit Kit ligand(KITLG) ELISA kit
E04K0089-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Kit ligand(KITLG) ELISA kit
E04K0089-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Kit ligand(KITLG) ELISA kit
E04K0089-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Kit ligand(KITLG) ELISA kit
E01K0089-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Kit ligand(KITLG) ELISA kit
E01K0089-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Kit ligand(KITLG) ELISA kit
E01K0089-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine KITLG/ Kit ligand ELISA Kit
E0164Bo	Sunlong	1 Kit	EUR 860.4

Mouse Kit ligand(KITLG) ELISA kit
E03K0089-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Kit ligand(KITLG) ELISA kit
E03K0089-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Kit ligand(KITLG) ELISA kit
E03K0089-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human KITLG(Kit ligand ) ELISA Kit
EH0514	FN Test	96T	EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Monkey Kit ligand(KITLG) ELISA kit
E09K0089-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Kit ligand(KITLG) ELISA kit
E09K0089-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Kit ligand(KITLG) ELISA kit
E09K0089-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human KITLG/ Kit ligand ELISA Kit
E1378Hu	Sunlong	1 Kit	EUR 644.4

Mouse Kitlg/ Kit ligand ELISA Kit
E1654Mo	Sunlong	1 Kit	EUR 655.2

Rat Kit ligand(KITLG) ELISA kit
E02K0089-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Kit ligand(KITLG) ELISA kit
E02K0089-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Kit ligand(KITLG) ELISA kit
E02K0089-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Kit ligand(KITLG) ELISA kit
E08K0089-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Kit ligand(KITLG) ELISA kit
E08K0089-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Kit ligand(KITLG) ELISA kit
E08K0089-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kit ligand(KITLG) ELISA kit
E07K0089-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kit ligand(KITLG) ELISA kit
E07K0089-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Kit ligand(KITLG) ELISA kit
E07K0089-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Kit Ligand (KITLG) Antibody
20-abx006306	Abbexa	EUR 493.20 EUR 710.40 EUR 218.40 EUR 376.80	100 ul 200 ul 20 ul 50 ul

Kit Ligand (KITLG) Antibody
abx122984-100ug	Abbexa	100 ug	EUR 469.2

Kit Ligand (KITLG) Antibody
20-abx125169	Abbexa	EUR 594.00 EUR 844.80	100 ul 200 ul

Kit Ligand (KITLG) Antibody
20-abx321525	Abbexa	EUR 360.00 EUR 292.80	100 ul 50 ul

Kit ligand (KITLG) Antibody
abx330456-100ul	Abbexa	100 ul	EUR 510

Human Kit ligand (KITLG)
1-CSB-EP012376HU	Cusabio	EUR 456.00 EUR 256.80 EUR 1570.80 EUR 672.00 EUR 1047.60 EUR 314.40	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Kit ligand(KITLG),partial expressed in E.coli

Kit ligand/KITLG/SCF
E21-D53	EnoGene	10ug	EUR 411.6

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS400A-KIT	SBI	1 kit (10 rxn)	EUR 1332

Pesticide Kit Containing All 10 Multi-Compound Mixes
SPXPR-KIT	Scientific Laboratory Supplies	1ML	EUR 1923.18

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS410A-KIT	SBI	1 kit (10 rxn)	EUR 798

Cas9-EGFP Protein and T7 gRNA SmartNuclease Synthesis Kit
CAS420A-KIT	SBI	1 kit (10 rxn)	EUR 828

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV100PA-KIT	SBI	1 Kit	EUR 1358.4

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV105PA-KIT	SBI	1 Kit	EUR 1358.4

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV120PA-KIT	SBI	1 Kit	EUR 1358.4

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit
CASLV125PA-KIT	SBI	1 Kit	EUR 1358.4

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS700A-KIT	SBI	10 rxn	EUR 1358.4

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS720A-KIT	SBI	10 rxn	EUR 1358.4

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector
CAS740A-KIT	SBI	10 rxn	EUR 1358.4

Guinea pig Kit ligand(KITLG) ELISA kit
E05K0089-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Guinea pig Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Kit ligand(KITLG) ELISA kit
E05K0089-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Guinea pig Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Kit ligand(KITLG) ELISA kit
E05K0089-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Guinea pig Kit ligand(KITLG) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

ELISA kit for Pig Kit ligand (KITLG)
KTE80143-48T	Abbkine	48T	EUR 424.8
Description: Quantitative sandwich ELISA for measuring Pig Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Pig Kit ligand (KITLG)
KTE80143-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Pig Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Pig Kit ligand (KITLG)
KTE80143-96T	Abbkine	96T	EUR 686.4
Description: Quantitative sandwich ELISA for measuring Pig Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Kit ligand (KITLG)
KTE10341-96T	Abbkine	96T	EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Canine Kit ligand (KITLG)
KTE20076-48T	Abbkine	48T	EUR 424.8
Description: Quantitative sandwich ELISA for measuring Canine Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Canine Kit ligand (KITLG)
KTE20076-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Canine Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Canine Kit ligand (KITLG)
KTE20076-96T	Abbkine	96T	EUR 686.4
Description: Quantitative sandwich ELISA for measuring Canine Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Kit ligand (KITLG)
KTE10341-48T	Abbkine	48T	EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Kit ligand (KITLG)
KTE10341-5platesof96wells	Abbkine	5 plates of 96 wells	EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Kit ligand (KITLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)
CAS510A-KIT	SBI	1 Kit	EUR 966

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV200PA-KIT	SBI	1 Kit	EUR 1358.4

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV205PA-KIT	SBI	1 Kit	EUR 1358.4

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV220PA-KIT	SBI	1 Kit	EUR 1358.4

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit
CASLV225PA-KIT	SBI	1 Kit	EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS750A-KIT	SBI	10 rxn	EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS770A-KIT	SBI	10 rxn	EUR 1358.4

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector
CAS790A-KIT	SBI	10 rxn	EUR 1358.4

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]
CAS9LIG-KIT	SBI	1 Kit	EUR 183.6

c-kit Ligand/SCF/KITLG
E21-034	EnoGene	10ug	EUR 411.6

Claritas PPT Grade Minerals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL
SPXMT-KIT	Scientific Laboratory Supplies	30ML	EUR 237.12

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)
PIN320A-KIT	SBI	1 Kit	EUR 5929.2

Claritas PPT Grade Heavy Metals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL
SPXHM-KIT	Scientific Laboratory Supplies	30ML	EUR 245.1

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)
PIN340iPS-KIT	SBI	1 Kit	EUR 5929.2

AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE620A-KIT	SBI	1 kit	EUR 2558.4

AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE622A-KIT	SBI	1 kit	EUR 2558.4

AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)
GE624A-KIT	SBI	1 kit	EUR 2558.4

ExoAb Antibody Kit (CD9, CD63, CD81, Hsp70 antibodies, rabbit anti-human) with goat anti-rabbit HRP secondary antibody
EXOAB-KIT-1	SBI	25 ul each	EUR 752.4

vWF Acty. Kit
ABP-ACT-KIT	Abpcorp	12 x 8 microwells	EUR 513.6

vWF Ant. Kit
ABP-TOT-KIT	Abpcorp	12 x 8 microwells	EUR 472.8

PrecisionX Multiplex gRNA Cloning Kit
CAS9-GRNA-KIT	SBI	10 rxn	EUR 534

hspCas9 AAVS1 Safe Harbor Knock-in Donor (AAVS1-SA-puro-EF1-hspCas9)
CAS620A-KIT	SBI	1 kit	EUR 2582.4
Description: Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector), CAS640PR-1 (Junction PCR Primer Mix to confirm Cas9 integration site), and CAS9-PR-1 (PCR primers to confirm Cas9 expression)

PinPoint-FC System for Platform Cell Line Generation & Retargeting (includes PIN300A-1, FC200PA-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PIN300A-KIT	SBI	1 Kit	EUR 3357.6

PinPoint-HR System for Platform Cell Line Generation & Retargeting (includes PIN400A-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PIN400A-KIT	SBI	1 Kit	EUR 3357.6

PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, GE601A-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PIN410A-KIT	SBI	1 Kit	EUR 5202

PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, CAS601A-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PIN412A-KIT	SBI	1 Kit	EUR 5202

Filtration System 47mm Complete Assembly
5809/KIT	Scientific Laboratory Supplies	EACH	EUR 427.69

mRNAExpress mRNA Synthesis kit (5 reactions)
MR-KIT-1	SBI	5 reactions	EUR 1382.4

42 Component Terpene Kit in Methanol
CAN-TERP-KIT	Scientific Laboratory Supplies	1ML	EUR 287.28

Canadian Pesticide Kit Containing All 6 Mixes
CAN-CAN-KIT	Scientific Laboratory Supplies	1ML	EUR 758.1

AxioCam Erc5s rev 2, w/Accessory Kit
ZV-Erc5sAC-Kit	MiTeGen	1 KIT	EUR 1611
Description: AxioCam Erc5s rev 2, w/Accessory Kit- connection cable Y-USB 2.0.- HDMI cable to DVI-D- SD card- IR remote control

KITLG ELISA KIT|Human
EF000332	Lifescience Market	96 Tests	EUR 826.8

Human KitLG ELISA Kit
ELA-E0120h	Lifescience Market	96 Tests	EUR 988.8

Goat FAS Ligand ELISA kit
E06F0051-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat FAS Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat FAS Ligand ELISA kit
E06F0051-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat FAS Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat FAS Ligand ELISA kit
E06F0051-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat FAS Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD30 Ligand ELISA kit
E06C0335-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat CD30 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD30 Ligand ELISA kit
E06C0335-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat CD30 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD30 Ligand ELISA kit
E06C0335-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat CD30 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

CLOuD9 Gene Expression Regulation Kit (includes 10 ug each of dCas9-PYL1 and dCas9-ABI1 lentivectors, and 100 ul of 0.5M Inducer Agent)
CASCL9-100A-KIT	SBI	1 Kit	EUR 1358.4

pPACK-SPIKE Combo Kit, includes Cat# CVD19-500A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-520A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE D614G Combo Kit, includes Cat# CVD19-530A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-550A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE N501Y Combo Kit, includes Cat# CVD19-560A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-575A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE Alpha Combo Kit, includes Cat# CVD19-590A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-599A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE Gamma Combo Kit, includes Cat# CVD19-630A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-639A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE Beta Combo Kit, includes Cat# CVD19-640A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-649A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE Delta Combo Kit, includes Cat# CVD19-650A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-659A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE Omicron Combo Kit, includes Cat# CVD19-660A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-669A-KIT	SBI	1 kit	EUR 1162

Human Ghrelin-O-Acyltransferase (GOAT) ELISA Kit
DLR-GOAT-Hu-48T	DL Develop	48T	EUR 664.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Ghrelin-O-Acyltransferase (GOAT) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Ghrelin-O-Acyltransferase (GOAT) ELISA Kit
DLR-GOAT-Hu-96T	DL Develop	96T	EUR 870
Description: A sandwich quantitative ELISA assay kit for detection of Human Ghrelin-O-Acyltransferase (GOAT) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Ghrelin-O-Acyltransferase (GOAT) ELISA Kit
RDR-GOAT-Hu-48Tests	Reddot Biotech	48 Tests	EUR 706.8

Human Ghrelin-O-Acyltransferase (GOAT) ELISA Kit
RDR-GOAT-Hu-96Tests	Reddot Biotech	96 Tests	EUR 984

Human Ghrelin-O-Acyltransferase (GOAT) ELISA Kit
RD-GOAT-Hu-48Tests	Reddot Biotech	48 Tests	EUR 675.6

Human Ghrelin-O-Acyltransferase (GOAT) ELISA Kit
RD-GOAT-Hu-96Tests	Reddot Biotech	96 Tests	EUR 939.6

pPACK-SPIKE B.1.429 Combo Kit, includes Cat# CVD19-610A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-619A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE B.1.525 Combo Kit, includes Cat# CVD19-620A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-629A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE B.1.351 RBD Mutations Combo Kit, includes Cat# CVD19-580A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-589A-KIT	SBI	1 kit	EUR 1141

pPACK-SPIKE B.1.351 S1 Mutations Combo Kit, includes Cat# CVD19-600A-1, plus PureFection Transfection Reagent (Cat# LV750A-1) and PEG-it Virus Concentration solution (Cat# LV810A-1)
CVD19-609A-KIT	SBI	1 kit	EUR 1141

Goat soluble OX40 Ligand ELISA kit
E06S0320-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat soluble OX40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat soluble OX40 Ligand ELISA kit
E06S0320-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat soluble OX40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat soluble OX40 Ligand ELISA kit
E06S0320-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat soluble OX40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD 40 Ligand ELISA kit
E06C0018-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat CD 40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD 40 Ligand ELISA kit
E06C0018-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat CD 40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CD 40 Ligand ELISA kit
E06C0018-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat CD 40 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

KITLG ELISA Kit (Human) (OKBB00735)
OKBB00735	Aviva Systems Biology	96 Wells	EUR 606
Description: Description of target: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). It is mapped to 12q21.32. SCF was primarily expressed by perivascular cells throughout the bone marrow, and it plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. SCF can exist both as a transmembrane protein and a soluble protein. This gene plays an important role in the hematopoiesis during embryonic development. During development, the presence of the SCF also plays an important role in the localization of melanocytes, cells that produce melanin and control pigmentation. In addition to it, SCF can promote mast cell adhesion, migration, proliferation, and survival. It also promotes the release of histamine and tryptase, which are involved in the allergic response.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

KITLG ELISA Kit (Rat) (OKBB00736)
OKBB00736	Aviva Systems Biology	96 Wells	EUR 606
Description: Description of target: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). It is mapped to 12q21.32. SCF was primarily expressed by perivascular cells throughout the bone marrow, and it plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. SCF can exist both as a transmembrane protein and a soluble protein. This gene plays an important role in the hematopoiesis during embryonic development. During development, the presence of the SCF also plays an important role in the localization of melanocytes, cells that produce melanin and control pigmentation. In addition to it, SCF can promote mast cell adhesion, migration, proliferation, and survival. It also promotes the release of histamine and tryptase, which are involved in the allergic response.;Species reactivity: Rat;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

KITLG ELISA Kit (Mouse) (OKBB00737)
OKBB00737	Aviva Systems Biology	96 Wells	EUR 606
Description: Description of target: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). It is mapped to 12q21.32. SCF was primarily expressed by perivascular cells throughout the bone marrow, and it plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. SCF can exist both as a transmembrane protein and a soluble protein. This gene plays an important role in the hematopoiesis during embryonic development. During development, the presence of the SCF also plays an important role in the localization of melanocytes, cells that produce melanin and control pigmentation. In addition to it, SCF can promote mast cell adhesion, migration, proliferation, and survival. It also promotes the release of histamine and tryptase, which are involved in the allergic response.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

KITLG ELISA Kit (Chicken) (OKEH07311)
OKEH07311	Aviva Systems Biology	96 Wells	EUR 1420.8
Description: Description of target: ;Species reactivity: Chicken;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 39pg/mL

KITLG ELISA Kit (Dog) (OKEH07312)
OKEH07312	Aviva Systems Biology	96 Wells	EUR 1420.8
Description: Description of target: ;Species reactivity: Dog;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 39pg/mL

KITLG ELISA Kit (Pig) (OKEH07313)
OKEH07313	Aviva Systems Biology	96 Wells	EUR 1310.4
Description: Description of target: ;Species reactivity: Pig;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 39pg/mL

KITLG ELISA Kit (Human) (OKAN04599)
OKAN04599	Aviva Systems Biology	96 Wells	EUR 950.4
Description: Description of target: This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.5 pg/mL

KITLG ELISA Kit (Mouse) (OKEH04054)
OKEH04054	Aviva Systems Biology	96 Wells	EUR 652.8
Description: Description of target: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.039 ng/mL

Kitlg ELISA Kit (Rat) (OKEH04516)
OKEH04516	Aviva Systems Biology	96 Wells	EUR 652.8
Description: Description of target: Soluble growth factor that activates c-kit tyrosine kinase receptor; important for signaling in spermatogenesis; putative regulator of Leydig cell development.;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 15.78 pg/mL

KITLG ELISA Kit (Bovine) (OKEH04606)
OKEH04606	Aviva Systems Biology	96 Wells	EUR 934.8
Description: Description of target: Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins..;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 30 pg/mL

KITLG ELISA Kit (Bovine) (OKCD05997)
OKCD05997	Aviva Systems Biology	96 Wells	EUR 1248
Description: Description of target: Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins..;Species reactivity: Bovine;Application: ELISA;Assay info: ;Sensitivity: < 5.7pg/mL

KITLG ELISA Kit (Dog) (OKCD05998)
OKCD05998	Aviva Systems Biology	96 Wells	EUR 1201.2
Description: Description of target: This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Dog;Application: ELISA;Assay info: ;Sensitivity: < 6.5pg/mL

KITLG ELISA Kit (Human) (OKCD05999)
OKCD05999	Aviva Systems Biology	96 Wells	EUR 777.6
Description: Description of target: KITLG is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis.This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 6.5pg/mL

KITLG ELISA Kit (Pig) (OKCD06001)
OKCD06001	Aviva Systems Biology	96 Wells	EUR 1248
Description: Description of target: This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Pig;Application: ELISA;Assay info: ;Sensitivity: < 6.4pg/mL

KITLG ELISA Kit (Rat) (OKCD06002)
OKCD06002	Aviva Systems Biology	96 Wells	EUR 981.6
Description: Description of target: soluble growth factor that activates c-kit tyrosine kinase receptor; important for signaling in spermatogenesis; putative regulator of Leydig cell development.;Species reactivity: Rat;Application: ELISA;Assay info: ;Sensitivity: < 6.3pg/mL

42 Component Terpene Kit High Level in Methanol
CAN-TERP-KIT-H	Scientific Laboratory Supplies	1ML	EUR 308.94

Assurance Grade Set of 38 Single-Element Standards 1000 ug/mL (1000 PPM)
ICP-KIT-1	Scientific Laboratory Supplies	EACH	EUR 1914.06

AXYGEN® AXYPET® PRO STARTER KIT: 4 PIPETTORS, PLEXI STAND, SAMPLE TIPS
AP-STR-KIT-P	CORNING	1/pk	EUR 865.2
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Goat CXC chemokine ligand 13 ELISA kit
E06C2556-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 13 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CXC chemokine ligand 13 ELISA kit
E06C2556-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 13 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CXC chemokine ligand 13 ELISA kit
E06C2556-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 13 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CXC chemokine ligand 16 ELISA kit
E06C0851-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 16 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CXC chemokine ligand 16 ELISA kit
E06C0851-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 16 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CXC chemokine ligand 16 ELISA kit
E06C0851-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 16 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CXC chemokine ligand 10 ELISA kit
E06C0856-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 10 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CXC chemokine ligand 10 ELISA kit
E06C0856-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 10 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat CXC chemokine ligand 10 ELISA kit
E06C0856-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat CXC chemokine ligand 10 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat A Proliferation inducing ligand ELISA kit
E06A0051-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat A Proliferation inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat A Proliferation inducing ligand ELISA kit
E06A0051-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat A Proliferation inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat A Proliferation inducing ligand ELISA kit
E06A0051-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat A Proliferation inducing ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

AXYPET STARTER KIT 1 AP-20, AP-200 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS
AP-STR-KIT-1	CORNING	1/pk	EUR 426
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET STARTER KIT 2 AP-10, AP-100 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS
AP-STR-KIT-2	CORNING	1/pk	EUR 440.4
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Goat P selectin glycoprotein ligand 1 ELISA kit
E06P0114-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat P selectin glycoprotein ligand 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat P selectin glycoprotein ligand 1 ELISA kit
E06P0114-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat P selectin glycoprotein ligand 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat P selectin glycoprotein ligand 1 ELISA kit
E06P0114-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat P selectin glycoprotein ligand 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat a prolifeion inducing ligand(APRIL) ELISA kit
E06A2010-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat a prolifeion inducing ligand(APRIL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat a prolifeion inducing ligand(APRIL) ELISA kit
E06A2010-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat a prolifeion inducing ligand(APRIL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat a prolifeion inducing ligand(APRIL) ELISA kit
E06A2010-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat a prolifeion inducing ligand(APRIL) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

KITLG Chemi-Luminescent ELISA Kit (Human) (OKCD03912)
OKCD03912	Aviva Systems Biology	96 Wells	EUR 1185.6
Description: Description of target: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins. ;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 31.2 pg/mL

KITLG ELISA Kit (Human) : 96 Wells (OKEH00202)
OKEH00202	Aviva Systems Biology	96 Wells	EUR 652.8
Description: Description of target: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 12 pg/mL

Custom Antibody titration by ELISA up to 2 rabbits and 1 bleed
ELISA-1	Alpha Diagnostics	1	EUR 242.4

Goat Soluble cluster of differentiation 30 ligand ELISA kit
E06S0238-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Soluble cluster of differentiation 30 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Soluble cluster of differentiation 30 ligand ELISA kit
E06S0238-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Soluble cluster of differentiation 30 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Soluble cluster of differentiation 30 ligand ELISA kit
E06S0238-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Soluble cluster of differentiation 30 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Chemokine C-C motif ligand 20 ELISA kit
E06C2513-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Chemokine C-C motif ligand 20 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Chemokine C-C motif ligand 20 ELISA kit
E06C2513-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Chemokine C-C motif ligand 20 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Chemokine C-C motif ligand 20 ELISA kit
E06C2513-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Chemokine C-C motif ligand 20 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Cluster of Differentiation 40 Ligand Antibody ELISA kit
E06C2557-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Cluster of Differentiation 40 Ligand Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Cluster of Differentiation 40 Ligand Antibody ELISA kit
E06C2557-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Cluster of Differentiation 40 Ligand Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Cluster of Differentiation 40 Ligand Antibody ELISA kit
E06C2557-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Cluster of Differentiation 40 Ligand Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat FMS Like Tyrosine Kinase 3 Ligand ELISA kit
E06F0108-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat FMS Like Tyrosine Kinase 3 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat FMS Like Tyrosine Kinase 3 Ligand ELISA kit
E06F0108-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat FMS Like Tyrosine Kinase 3 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat FMS Like Tyrosine Kinase 3 Ligand ELISA kit
E06F0108-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat FMS Like Tyrosine Kinase 3 Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat FMS-like tyrosine kinase 3 ligand ELISA kit
E06F0228-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat FMS-like tyrosine kinase 3 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat FMS-like tyrosine kinase 3 ligand ELISA kit
E06F0228-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat FMS-like tyrosine kinase 3 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat FMS-like tyrosine kinase 3 ligand ELISA kit
E06F0228-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat FMS-like tyrosine kinase 3 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Chemokine C C motif ligand 18 ELISA kit
E06C0064-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Chemokine C C motif ligand 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Chemokine C C motif ligand 18 ELISA kit
E06C0064-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Chemokine C C motif ligand 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Chemokine C C motif ligand 18 ELISA kit
E06C0064-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Chemokine C C motif ligand 18 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat soluble Cluster of differentiation 40 ligand ELISA kit
E06C0209-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat soluble Cluster of differentiation 40 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat soluble Cluster of differentiation 40 ligand ELISA kit
E06C0209-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A competitive ELISA for quantitative measurement of Goat soluble Cluster of differentiation 40 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat soluble Cluster of differentiation 40 ligand ELISA kit
E06C0209-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A competitive ELISA for quantitative measurement of Goat soluble Cluster of differentiation 40 ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Prawidłowe poziomy sIgA jelitowego po długotrwałym leczeniu szczepami L. lactis niosącymi plazmidy kodujące IL-4 i IL-10 wskazują na rozwój tolerancji doustnej i potwierdzają zastosowanie tego silnego narzędzia do dostarczania przez śluzówkę. Po raz pierwszy szczepy L. lactis MG1363 FnBPA + niosące eukariotyczne wektory ekspresyjne kodujące IL-4 i IL-10 testowano w mysich modelach indukowanych STZ i NOD. Dlatego nasze badanie pokazuje, że ta innowacyjna strategia zapewnia potencjał immunomodulacyjny do dalszych badań nad T1D i innymi chorobami autoimmunologicznymi.