Cukrzyca jest jedną z najszybciej rozwijających się chorób niezakaźnych. Cukrzyca jest spowodowana zniszczeniem komórek beta trzustki lub z insulinoopornością i charakteryzuje się hiperglikemią. Cukrzyca powoduje bardzo poważny kryzys gospodarczy, ponieważ rynek leków na cukrzycę rozwija się bardzo szybko. Nawet po przełomowych odkryciach naukowych, dostępności lepszej infrastruktury opieki zdrowotnej, wzroście poziomu umiejętności czytania i pisania, ciężar cukrzycy stale rozprzestrzenia się w różnych sekcjach na całym świecie, a zwłaszcza w krajach o niskich i średnich dochodach.
Niedawny rozwój odkryć naukowych zaowocował powstaniem szeregu nowych generacji leków przeciwcukrzycowych, takich jak sulfonylomocznik, biguanidy, tiazolidynodion, inhibitory alfa glukozydazy. Wszystkie te leki wykazały znaczące obniżenie poziomu glukozy we krwi. Opracowano również i opisano kilka nowych klas leków hipoglikemizujących, takich jak analogi GLP-1, inhibitory DPP-IV, inhibitory amyliny, receptory aktywowane przez proliferatory peroksysomów.
Istnieją pewne aktywne cząsteczki i substancje bioaktywne zostały oczyszczone z ziół i roślin, co dodaje wartości do wojny z cukrzycą. Te fitokomponenty zniweczyły rozwój leków i doprowadziły do identyfikacji leków na cukrzycę. Przegląd koncentruje się również na niektórych krytycznych obszarach cukrzycy, ze szczególnym uwzględnieniem podejścia do leczenia cukrzycy opartego na statynach oraz terapii przeciwcukrzycowej nowej generacji opartej na komórkach macierzystych.
Otyłość, cukrzyca typu 2 i ryzyko raka
Otyłość i cukrzyca typu 2 są związane ze zwiększonym ryzykiem raka i stają się coraz częstsze. Nieprawidłowości metaboliczne, takie jak insulinooporność i dyslipidemia, są związane zarówno z otyłością, jak i cukrzycą typu 2 i mają wpływ na związek otyłość-rak. Zaproponowano wiele mechanizmów łączących otyłość i cukrzycę z progresją raka, w tym wzrost sygnalizacji insuliny / IGF-1, wychwytu i metabolizmu lipidów i glukozy, zmiany w profilu cytokin, chemokin i adipokin, a także zmiany w tkanka tłuszczowa bezpośrednio sąsiadująca z miejscami raka. Niniejszy przegląd ma na celu podsumowanie i przedstawienie aktualnych danych epidemiologicznych i mechanistycznych łączących otyłość i cukrzycę typu 2 z rakiem, ze szczególnym uwzględnieniem roli insuliny, lipidów i tkanki tłuszczowej.
Słodki i słony: cukrzycowa kwasica ketonowa u pacjenta z nefrogenną cukrzycą prostą
Współwystępowanie nefrogennej moczówki prostej (NDI) z cukrzycą (DM) u pacjenta z cukrzycową kwasicą ketonową (DKA) jest rzadkie i, według naszej wiedzy, nie zostało opisane nawet w opisach przypadków. Przedstawiamy przypadek 16-letniego mężczyzny ze znanym NDI, który zgłosił się na jeden dzień na oddział ratunkowy (SOR) u dzieci z uogólnionym osłabieniem i zmniejszonym apetytem, u którego stwierdzono umiarkowaną CKK po pojawieniu się DM.
Początkowe leczenie odwodnienia i stanu hiperosmolarnego stanowiło wyjątkowe wyzwanie. Resuscytacja płynami izotonicznymi płynami u pacjenta z NDI stwarza ryzyko nasilenia hipernatremii, co może prowadzić do drgawek i śmierci. Jednak stosowanie płynów hipotonicznych może zbyt szybko obniżyć osmolalność surowicy, co może skutkować obrzękiem mózgu.
Konsultanci nefrologii, endokrynologii i pediatrycznego oddziału intensywnej opieki medycznej (PICU) zostali powiadomieni o tym pacjencie i skoordynowano dyskusję między pod-specjalistami w celu ustalenia odpowiedniej resuscytacji płynowej. Pacjentowi pozwolono pić bezpłatną wodę oprócz dożylnych płynów (IVF) 5% dekstrozy z 0,2% chlorkiem sodu z szybkością półtorej dawki podtrzymującej (150 ml / godz.) Na SOR przed transferem na OIT, gdzie rozpoczęto wlew insuliny. Ten opis przypadku zawiera wytyczne dla personelu szpitalnego dotyczące postępowania z pacjentami ze współistniejącymi NDI i DM w DKA, rzadkim połączeniu, które wymaga przemyślanego i pilnego leczenia.

Sygnatura mikroRNA osocza związana z retinopatią u pacjentów z cukrzycą typu 2
Retinopatia cukrzycowa (DR) jest główną przyczyną utraty wzroku i niepełnosprawności. Skuteczne leczenie DR zależy od szybkiego leczenia i przyniosłoby korzyści z biomarkerów do badań przesiewowych i przedobjawowego wykrywania retinopatii u pacjentów z cukrzycą. MikroRNA (miRNA) to post-transkrypcyjne regulatory ekspresji genów, które są uwalniane we krwi i mogą służyć jako biomarkery. Niewiele wiadomo na temat krążących miRNA u pacjentów z cukrzycą typu 2 (T2DM) i DR.
Tutaj pokazujemy, że DR jest związane z wyższym krążącym miR-25-3p (P = 0,004) i miR-320b (P = 0,011) oraz niższymi poziomami miR-495-3p (P <0,001) w kohorcie pacjentów z T2DM z DR (n = 20), w porównaniu z osobami z cukrzycą bez DR (n = 10) i osobami zdrowymi (n = 10). Zależności te utrzymywały się znaczące po dostosowaniu do wieku, płci i HbA1c. Poziomy krążących miRNA korelowały z ciężkością choroby, a ich towarzysząca ocena wykazała wysoką dokładność identyfikacji DR (AUROC = 0,93; P <0,001).
Analiza ontologii genów zweryfikowanych celów wykazała wzbogacenie szlaków, takich jak regulacja procesów metabolicznych (P = 1,5 × 10-20), odpowiedź komórek na stres (P = 1,9 × 10-14) i rozwój naczyń krwionośnych (P = 2,7 × 10-14). W oczekiwaniu na zewnętrzną walidację spodziewamy się, że te miRNA mogą służyć jako domniemane biomarkery choroby i uwydatniać nowe cele molekularne w celu poprawy opieki nad pacjentami z retinopatią cukrzycową.
Rola sygnalizacji receptora komórek T w rozwoju cukrzycy typu 1
Sygnalizacja receptora komórek T (TCR) wpływa na wiele aspektów immunobiologii limfocytów T CD4 + i CD8 +, w tym rozwój grasicy, homeostazę obwodową, różnicowanie / funkcję podzbiorów efektorowych i tworzenie pamięci. Dodatkowe wskazówki sygnalizacyjne komórek T wyzwalane przez cząsteczki kostymulujące i cytokiny również wpływają na czas trwania sygnalizacji TCR, a także dodatkowe szlaki, które dodatkowo kształtują odpowiedź komórek T.
Cukrzyca typu 1 (T1D) jest chorobą autoimmunologiczną kierowaną przez komórki T, której celem są komórki β trzustki wytwarzające insulinę. Dowody wskazują, że rozregulowane zdarzenia sygnalizacyjne TCR w T1D wpływają na skuteczność ośrodkowych i obwodowych mechanizmów wywołujących tolerancję.
TDP43 ELISA Kit| Mouse TAR DNA Binding Protein 43 ELISA Kit |
EF013922 |
Lifescience Market |
96 Tests |
EUR 826.8 |
ELISA kit for Mouse TDP43 (TAR DNA Binding Protein 43) |
E-EL-M1115 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
Description: A sandwich ELISA kit for quantitative measurement of Mouse TDP43 (TAR DNA Binding Protein 43) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Human TDP43 (TAR DNA Binding Protein 43) |
E-EL-H0942 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 640.8 |
|
Description: A sandwich ELISA kit for quantitative measurement of Human TDP43 (TAR DNA Binding Protein 43) in samples from Serum, Plasma, Cell supernatant |
Tar DNA Binding Protein 43 kDa (TDP43) Antibody |
20-abx103209 |
Abbexa |
-
EUR 493.20
-
EUR 159.60
-
EUR 1378.80
-
EUR 678.00
-
EUR 376.80
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Tar DNA Binding Protein 43 kDa (TDP43) Antibody |
20-abx103210 |
Abbexa |
-
EUR 510.00
-
EUR 159.60
-
EUR 1412.40
-
EUR 693.60
-
EUR 393.60
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Tar DNA Binding Protein 43 kDa (TDP43) Antibody |
20-abx174716 |
Abbexa |
|
|
|
Human Tar DNA Binding Protein 43 kDa (TDP43) Protein |
20-abx069231 |
Abbexa |
-
EUR 828.00
-
EUR 343.20
-
EUR 2532.00
-
EUR 978.00
-
EUR 594.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Mouse Tar DNA Binding Protein 43 kDa (TDP43) Protein |
20-abx069232 |
Abbexa |
-
EUR 844.80
-
EUR 343.20
-
EUR 2598.00
-
EUR 994.80
-
EUR 594.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Human Tar DNA Binding Protein 43 kDa (TDP43) CLIA Kit |
abx197753-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
DLR-TDP43-Hu-48T |
DL Develop |
48T |
EUR 597.6 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Tar DNA Binding Protein 43kDa (TDP43) in samples from serum, plasma, cerebrospinal fluid or other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
DLR-TDP43-Hu-96T |
DL Develop |
96T |
EUR 776.4 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Human Tar DNA Binding Protein 43kDa (TDP43) in samples from serum, plasma, cerebrospinal fluid or other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
SEB951Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 5402.92 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tar DNA Binding Protein 43kDa (TDP43) in serum, plasma, cerebrospinal fluid and other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
SEB951Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 550.13 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tar DNA Binding Protein 43kDa (TDP43) in serum, plasma, cerebrospinal fluid and other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
SEB951Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 734.46 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tar DNA Binding Protein 43kDa (TDP43) in serum, plasma, cerebrospinal fluid and other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
SEB951Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2945.08 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tar DNA Binding Protein 43kDa (TDP43) in serum, plasma, cerebrospinal fluid and other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
4-SEB951Hu |
Cloud-Clone |
-
EUR 5463.60
-
EUR 2886.00
-
EUR 735.60
|
- 10 plates of 96 wells
- 5 plates of 96 wells
- 1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Tar DNA Binding Protein 43kDa (TDP43) in samples from serum, plasma, cerebrospinal fluid and other biological fluids with no significant corss-reactivity with analogues from other species. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
RDR-TDP43-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 626.4 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
RDR-TDP43-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 868.8 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
RD-TDP43-Hu-48Tests |
Reddot Biotech |
48 Tests |
EUR 600 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
RD-TDP43-Hu-96Tests |
Reddot Biotech |
96 Tests |
EUR 830.4 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
DLR-TDP43-Hu |
DL Develop |
96T |
EUR 443 |
|
Description: serum, plasma, cerebrospinal fluid or other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
DL-TDP43-Hu |
DL Develop |
96T |
EUR 421 |
|
Description: serum, plasma, cerebrospinal fluid or other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
RDR-TDP43-Hu-48T |
Reddot Biotech |
48T |
EUR 453.92 |
|
Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
RDR-TDP43-Hu-96T |
Reddot Biotech |
96T |
EUR 648.38 |
|
Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
RD-TDP43-Hu-48T |
Reddot Biotech |
48T |
EUR 432.3 |
|
Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
RD-TDP43-Hu-96T |
Reddot Biotech |
96T |
EUR 617.5 |
|
Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
EKU07570-48T |
Biomatik Corporation |
48T |
EUR 527.66 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
EKU07570-5x96T |
Biomatik Corporation |
5x96T |
EUR 3580.55 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
EKU07570-96T |
Biomatik Corporation |
96T |
EUR 753.8 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
EKN48681-48T |
Biomatik Corporation |
48T |
EUR 359.87 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
EKN48681-5x96T |
Biomatik Corporation |
5x96T |
EUR 2441.98 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
EKN48681-96T |
Biomatik Corporation |
96T |
EUR 514.1 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
EKL60910-5x96T |
Biomatik Corporation |
5x96T |
EUR 3622.83 |
Human Tar DNA Binding Protein 43kDa (TDP43) ELISA Kit |
EKL60910-96T |
Biomatik Corporation |
96T |
EUR 762.7 |
Human TDP43(Tar DNA Binding Protein 43KDa) ELISA Kit |
EH3862 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
Human Tar DNA Binding Protein 43kDa ELISA Kit (TDP43) |
RK02369 |
Abclonal |
96 Tests |
EUR 625.2 |
Human TDP43(Tar DNA Binding Protein 43KDa) ELISA Kit |
EKF57728-48T |
Biomatik Corporation |
48T |
EUR 396.9 |
Human TDP43(Tar DNA Binding Protein 43KDa) ELISA Kit |
EKF57728-5x96T |
Biomatik Corporation |
5x96T |
EUR 2693.25 |
Human TDP43(Tar DNA Binding Protein 43kDa) ELISA Kit |
ELK2378-48T |
ELK Biotech |
48T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TDP43. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TDP43. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human TDP43, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TDP43 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Human TDP43(Tar DNA Binding Protein 43kDa) ELISA Kit |
ELK2378-96T |
ELK Biotech |
96T |
Ask for price |
|
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TDP43. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TDP43. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human TDP43, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TDP43 in the samples is then determined by comparing the OD of the samples to the standard curve. |
Human TAR DNA binding protein 43,TARDBP/TDP-43 ELISA Kit |
201-12-0334 |
SunredBio |
96 tests |
EUR 528 |
|
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human TAR DNA binding protein 43(TARDBP/TDP-43)ELISA Kit |
GA-E0350HM-48T |
GenAsia Biotech |
48T |
EUR 346.8 |
Human TAR DNA binding protein 43(TARDBP/TDP-43)ELISA Kit |
GA-E0350HM-96T |
GenAsia Biotech |
96T |
EUR 559.2 |
Mouse TAR DNA binding protein 43(TARDBP/TDP-43) ELISA Kit |
QY-E21735 |
Qayee Biotechnology |
96T |
EUR 448.8 |
Human TAR DNA binding protein 43(TARDBP/TDP-43)ELISA Kit |
QY-E04553 |
Qayee Biotechnology |
96T |
EUR 433.2 |
Human TAR DNA binding protein 43,TARDBP/TDP-43 ELISA Kit |
YLA0479HU-48T |
Shanghai YL Biotech |
48T |
EUR 435 |
Human TAR DNA binding protein 43,TARDBP/TDP-43 ELISA Kit |
YLA0479HU-96T |
Shanghai YL Biotech |
96T |
EUR 562.5 |
ELISA kit for Human TDP43 (Tar DNA Binding Protein 43kDa) |
ELK2378 |
ELK Biotech |
1 plate of 96 wells |
EUR 518.4 |
|
Description: A sandwich ELISA kit for detection of Tar DNA Binding Protein 43kDa from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Recombinant Tar DNA Binding Protein 43kDa (TDP43) |
4-RPB951Hu01 |
Cloud-Clone |
-
EUR 588.79
-
EUR 280.80
-
EUR 1877.95
-
EUR 705.98
-
EUR 1291.97
-
EUR 469.20
-
EUR 4514.88
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Tar DNA Binding Protein 43kDa expressed in: E.coli |
Recombinant Tar DNA Binding Protein 43kDa (TDP43) |
4-RPB951Mu01 |
Cloud-Clone |
-
EUR 603.84
-
EUR 285.60
-
EUR 1934.40
-
EUR 724.80
-
EUR 1329.60
-
EUR 480.00
-
EUR 4656.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Tar DNA Binding Protein 43kDa expressed in: E.coli |
Recombinant Tar DNA Binding Protein 43kDa (TDP43) |
RPU43947-100ug |
Biomatik Corporation |
100ug |
EUR 537.9 |
Recombinant Tar DNA Binding Protein 43kDa (TDP43) |
RPU43948-100ug |
Biomatik Corporation |
100ug |
EUR 554.4 |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody |
CAU25007-100ul |
Biomatik Corporation |
100ul |
EUR 229.4 |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody |
CAU25007-200ul |
Biomatik Corporation |
200ul |
EUR 287.3 |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody |
CAU25008-100ul |
Biomatik Corporation |
100ul |
EUR 222.7 |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody |
CAU25008-200ul |
Biomatik Corporation |
200ul |
EUR 278.9 |
CLIA kit for Human TDP43 (Tar DNA Binding Protein 43KDa ) |
E-CL-H0642 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 700.8 |
|
Description: A sandwich CLIA kit for quantitative measurement of Human TDP43 (Tar DNA Binding Protein 43KDa ) in samples from Serum, Plasma, Cell supernatant |
Tar DNA Binding Protein 43kDa (TDP43) Magnetic Luminex Assay Kit |
LKU601015-96T |
Biomatik Corporation |
96T |
EUR 917.7 |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Human) |
4-PAB951Hu01 |
Cloud-Clone |
-
EUR 286.80
-
EUR 2869.20
-
EUR 717.60
-
EUR 358.80
-
EUR 253.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Tar DNA Binding Protein 43kDa (TDP43) |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Mouse) |
4-PAB951Mu01 |
Cloud-Clone |
-
EUR 291.60
-
EUR 2948.40
-
EUR 735.60
-
EUR 366.00
-
EUR 254.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Tar DNA Binding Protein 43kDa (TDP43) |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Human), PE |
4-PAB951Hu01-PE |
Cloud-Clone |
-
EUR 344.40
-
EUR 3012.00
-
EUR 860.40
-
EUR 430.80
-
EUR 230.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with PE. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Mouse), PE |
4-PAB951Mu01-PE |
Cloud-Clone |
-
EUR 350.40
-
EUR 3098.40
-
EUR 882.00
-
EUR 439.20
-
EUR 232.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with PE. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Human), APC |
4-PAB951Hu01-APC |
Cloud-Clone |
-
EUR 399.60
-
EUR 3735.60
-
EUR 1046.40
-
EUR 507.60
-
EUR 258.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with APC. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Human), Cy3 |
4-PAB951Hu01-Cy3 |
Cloud-Clone |
-
EUR 483.60
-
EUR 4930.80
-
EUR 1345.20
-
EUR 627.60
-
EUR 294.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with Cy3. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Human), HRP |
4-PAB951Hu01-HRP |
Cloud-Clone |
-
EUR 366.00
-
EUR 3256.80
-
EUR 926.40
-
EUR 459.60
-
EUR 243.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with HRP. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Mouse), APC |
4-PAB951Mu01-APC |
Cloud-Clone |
-
EUR 408.00
-
EUR 3843.60
-
EUR 1072.80
-
EUR 518.40
-
EUR 260.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with APC. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Mouse), Cy3 |
4-PAB951Mu01-Cy3 |
Cloud-Clone |
-
EUR 493.20
-
EUR 5074.80
-
EUR 1381.20
-
EUR 642.00
-
EUR 297.60
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with Cy3. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Mouse), HRP |
4-PAB951Mu01-HRP |
Cloud-Clone |
-
EUR 373.20
-
EUR 3350.40
-
EUR 949.20
-
EUR 469.20
-
EUR 246.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with HRP. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Human), FITC |
4-PAB951Hu01-FITC |
Cloud-Clone |
-
EUR 344.40
-
EUR 3012.00
-
EUR 860.40
-
EUR 430.80
-
EUR 230.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with FITC. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Mouse), FITC |
4-PAB951Mu01-FITC |
Cloud-Clone |
-
EUR 350.40
-
EUR 3098.40
-
EUR 882.00
-
EUR 439.20
-
EUR 232.80
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with FITC. |
Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA kit |
CSB-E17007h-24T |
Cusabio |
1 plate of 24 wells |
EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human TAR DNA-binding protein 43 (TARDBP/TDP43) in samples from serum, plasma, cell culture supernates, cerebrospinalfluid (CSF). A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA kit |
1-CSB-E17007h |
Cusabio |
-
EUR 964.80
-
EUR 6118.80
-
EUR 3244.80
|
- 1 plate of 96 wells
- 10 plates of 96 wells each
- 5 plates of 96 wells each
|
|
Description: Quantitativesandwich ELISA kit for measuring Human TAR DNA-binding protein 43 (TARDBP/TDP43) in samples from serum, plasma, cell culture supernates, cerebrospinalfluid(CSF). Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA Kit |
KTE60478-96T5 |
Abbkine |
96 T×5 |
EUR 2629 |
Description: This Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA Kit employs a two-site sandwich ELISA to quantitate TARDBP. |
Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA Kit |
KTE60478-96T50 |
Abbkine |
96 T×50 |
EUR 24569 |
Description: This Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA Kit employs a two-site sandwich ELISA to quantitate TARDBP. |
Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA kit |
EKC41252-48T |
Biomatik Corporation |
48T |
EUR 535.99 |
Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA kit |
EKC41252-5x96T |
Biomatik Corporation |
5x96T |
EUR 3637.08 |
Human TAR DNA-binding protein 43 (TARDBP/TDP43) ELISA kit |
EKC41252-96T |
Biomatik Corporation |
96T |
EUR 765.7 |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Human), Biotinylated |
4-PAB951Hu01-Biotin |
Cloud-Clone |
-
EUR 363.60
-
EUR 2809.20
-
EUR 836.40
-
EUR 442.80
-
EUR 259.20
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with Biotin. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Mouse), Biotinylated |
4-PAB951Mu01-Biotin |
Cloud-Clone |
-
EUR 368.40
-
EUR 2888.40
-
EUR 856.80
-
EUR 450.00
-
EUR 260.40
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with Biotin. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Human), APC-Cy7 |
4-PAB951Hu01-APC-Cy7 |
Cloud-Clone |
-
EUR 656.40
-
EUR 7327.20
-
EUR 1948.80
-
EUR 872.40
-
EUR 372.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Human Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with APC-Cy7. |
Tar DNA Binding Protein 43kDa (TDP43) Polyclonal Antibody (Mouse), APC-Cy7 |
4-PAB951Mu01-APC-Cy7 |
Cloud-Clone |
-
EUR 672.00
-
EUR 7543.20
-
EUR 2002.80
-
EUR 894.00
-
EUR 378.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Tar DNA Binding Protein 43kDa (TDP43). This antibody is labeled with APC-Cy7. |
ELISA kit for Human TAR DNA-binding protein 43 (TARDBP/TDP43) |
KTE60478-48T |
Abbkine |
48T |
EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Human TAR DNA-binding protein 43 (TARDBP/TDP43) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human TAR DNA-binding protein 43 (TARDBP/TDP43) |
KTE60478-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human TAR DNA-binding protein 43 (TARDBP/TDP43) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human TAR DNA-binding protein 43 (TARDBP/TDP43) |
KTE60478-96T |
Abbkine |
96T |
EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Human TAR DNA-binding protein 43 (TARDBP/TDP43) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Rat TAR DNA Binding Protein 43 ELISA kit |
E02T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rat TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat TAR DNA Binding Protein 43 ELISA kit |
E02T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rat TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat TAR DNA Binding Protein 43 ELISA kit |
E02T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rat TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat TAR DNA Binding Protein 43 (TARDBP) ELISA Kit |
abx256037-96tests |
Abbexa |
96 tests |
EUR 904.8 |
|
Dog TAR DNA Binding Protein 43 ELISA kit |
E08T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Canine TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog TAR DNA Binding Protein 43 ELISA kit |
E08T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Canine TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog TAR DNA Binding Protein 43 ELISA kit |
E08T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Canine TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig TAR DNA Binding Protein 43 ELISA kit |
E07T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Porcine TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig TAR DNA Binding Protein 43 ELISA kit |
E07T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Porcine TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig TAR DNA Binding Protein 43 ELISA kit |
E07T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Porcine TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat TAR DNA Binding Protein 43 ELISA kit |
E06T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Goat TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat TAR DNA Binding Protein 43 ELISA kit |
E06T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Goat TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat TAR DNA Binding Protein 43 ELISA kit |
E06T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Goat TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse TAR DNA Binding Protein 43 ELISA kit |
E03T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse TAR DNA Binding Protein 43 ELISA kit |
E03T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse TAR DNA Binding Protein 43 ELISA kit |
E03T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Mouse TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human TAR DNA Binding Protein 43 ELISA kit |
E01T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Human TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human TAR DNA Binding Protein 43 ELISA kit |
E01T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Human TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human TAR DNA Binding Protein 43 ELISA kit |
E01T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Human TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit TAR DNA Binding Protein 43 ELISA kit |
E04T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit TAR DNA Binding Protein 43 ELISA kit |
E04T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit TAR DNA Binding Protein 43 ELISA kit |
E04T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey TAR DNA Binding Protein 43 ELISA kit |
E09T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Monkey TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey TAR DNA Binding Protein 43 ELISA kit |
E09T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Monkey TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey TAR DNA Binding Protein 43 ELISA kit |
E09T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Monkey TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
TAR DNA-Binding Protein 43 (TDP-43) Antibody |
abx238573-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
TAR DNA-Binding Protein 43 (TDP-43) Antibody |
abx238574-100ug |
Abbexa |
100 ug |
EUR 610.8 |
|
TAR DNA-Binding Protein 43 (TDP-43) Antibody |
abx238575-100ug |
Abbexa |
100 ug |
EUR 610.8 |
|
TAR DNA-Binding Protein 43 (TDP-43) Antibody |
abx238576-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
TAR DNA-Binding Protein 43 (TDP-43) Antibody |
abx238577-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
TAR DNA-Binding Protein 43 (TDP-43) Antibody |
abx431750-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
Pig TAR DNA Binding Protein 43 (TARDBP) ELISA Kit |
abx361185-96tests |
Abbexa |
96 tests |
EUR 990 |
|
Guinea pig TAR DNA Binding Protein 43 ELISA kit |
E05T0108-192T |
BlueGene |
192 tests |
EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig TAR DNA Binding Protein 43 ELISA kit |
E05T0108-48 |
BlueGene |
1 plate of 48 wells |
EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Guinea pig TAR DNA Binding Protein 43 ELISA kit |
E05T0108-96 |
BlueGene |
1 plate of 96 wells |
EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig TAR DNA Binding Protein 43 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human TAR DNA Binding Protein 43 (TARDBP) ELISA Kit |
abx253259-96tests |
Abbexa |
96 tests |
EUR 848.4 |
|
Mouse TAR DNA Binding Protein 43 (TARDBP) ELISA Kit |
abx254453-96tests |
Abbexa |
96 tests |
EUR 904.8 |
|
W tym przeglądzie omówimy, w jaki sposób siła i charakter zdarzeń sygnalizacyjnych TCR wpływają na rozwój samoreaktywnych limfocytów T i napędzają progresję T1D poprzez wpływ na ekspresję genów limfocytów T, zaangażowanie w linię i utrzymanie patogennej anty-własnej T funkcja efektorowa komórki.
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